The cannula was patent intravenous fluids were given through the same cannula for another 24 hours after the calcium infusion. The patient did not complain of pain or swelling during the infusion. Some proteins, such as myoglobin, may be toxic to the kidneys and cause acute renal failure.īecause our patient had hypocalcemia, he received 10 mL of 10% calcium chloride twice a day, 1 infused over 45 minutes, for 2 days, through an intravenous line placed on the ventral aspect of his left forearm. Three days after the patient presented with acute renal failure and rhabdomyolysis, white-yellow plaques with irregular but well-defined borders developed over the infusion site on his left forearm (arrows)Ī 37-year-old man presented with acute renal failure and rhabdomyolysis, the rapid breakdown of skeletal muscle fibers, which results in the release of muscle fiber contents into the bloodstream. In most cases, calcinosis is associated with hypercalcemia or hyperphosphatemia, but in this case it was related to infusion of calcium chloride. Because knowledge about the diagnosis and management of calcium extravasation–related injuries is limited, we offer a case report with discussion.
2011 28:339-341)Įxtravasation of calcium solutions may result in subcutaneous calcinosis, or calcinosis cutis, the deposition of calcium salt in subcutaneous tissue. If the injury is detected early, the best treatment options are light compression dressing and immobilization and elevation of the limb. Taking preventive measures is the most important step in avoiding calcium infusion–related complications. Extravasation of calcium may cause injury to subcutaneous tissue with several mechanisms, and various factors determine the extent of damage. The patient's lesions improved spontaneously over time, with no specific treatment and no complications. Although his calcium levels normalized, multiple subcutaneous indurated plaques developed over his infusion site, even though there was no evidence of leakage. A patient had rhabdomyolysis followed by acute renal failure and received calcium supplementation for hypocalcemia.
ABSTRACT: Extravasation of calcium solutions may result in subcutaneous calcinosis, also known as calcinosis cutis.
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